C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/228, 260/201
C07D 211/70 (2006.01) A61K 31/335 (2006.01) A61K 31/445 (2006.01) C07D 405/04 (2006.01)
Patent
CA 2018942
ABSTRACT: A piperidine derivative represented by the following general formula (I): Image (I) wherein R represents a hydrogen atom or a lower alkyl group; X represents -CH=CH-, -CH2CH2-, or -CH2O-; Y represents an alkylene group having 1 to 5 carbon atoms which may be optionally substituted with a lower alkyl group, or Y represents an -A-O-B- group wherein A and B are the same or different and each independently represents an alkylene group having 1 to 3 carbon atoms which may be optionally substituted with a lower alkyl group is disclosed. Also disclosed are a pharmacologically acceptable salt of a compound of formula (I), a method for preparation of a compound of formula (I), an antihistaminic and antiallergic agent comprising a compound of formula (I), a pharmaceutical composition comprising a compound of formula (I), and a method for the treatment of an allergic disease by administering a compound of formula (I). 47
Ito Yasuo
Kato Hideo
Koshinaka Eiichi
Nishino Hiroyuki
Ogawa Nobuo
Hokuriku Pharmaceutical Co. Ltd.
Johnson Douglas S. Q.c.
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