Piperidine derivatives

Details Piperidine derivatives Piperidine derivatives

C - Chemistry, Metallurgy

07

D

260/292.2

C07D 211/08 (2006.01) C07D 211/22 (2006.01) C07D 211/70 (2006.01)

Patent

CA 1123438

M-956 PIPERIDINE DERIVATIVES ABSTRACT OF THE DISCLOSURE Novel compounds of the following formula: Image wherein R1 is hydrogen or hydroxy; R2 is hydrogen; or R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; R3 is -CH3, -CH2OH, -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; and each of A and B is hydrogen or hydroxy; with the provisos that at least one of A or B is hydrogen and one of A or B is other than hydrogen when R9 is -CH3; and pharmaceutically acceptable salts thereof. The compounds are useful as anti-histamines, anti-allergy agents and bronchodilators. .

344020

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