Piperidine derivatives

Details Piperidine derivatives Piperidine derivatives

C - Chemistry, Metallurgy

07

D

260/292.2

C07D 211/32 (2006.01) C07D 211/22 (2006.01) C07D 211/70 (2006.01) C07D 211/82 (2006.01)

Patent

CA 1123439

M-820 PIPERIDINE DERIVATIVES ABSTRACT OF THE DISCLOSURE Pharmaceutically useful compounds of the following formula: Image wherein R1 represents hydrogen or hydroxy; R2 represents hydrogen; or R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is a positive whole integer of from 1 to 5; R3 is -CH3, -CH2OH, -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; and A and B are individually hydrogen or hydroxy; with the provisos that at least one of A or B is hydrogen and one of A or B is other than hydrogen when R3 is -CH3; and pharmaceuti- cally acceptable acid addition salts thereof. The com- pounds are useful as anti-histamines, anti-allergy agents and bronchodilators.

344022

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