C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/06 (2006.01) A61K 31/444 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/4535 (2006.01) A61K 31/4545 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/535 (2006.01) A61K 31/5377 (2006.01) A61K 31/54 (2006.01) A61K 38/05 (2006.01) C07D 211/70 (2006.01) C07D 401/02 (2006.01) C07D 401/12 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 413/06 (2006.01)
Patent
CA 2147429
A pharmaceutical composition for antagonizing serotonin or inhibiting platelet aggregation comprises as active ingredient a piperidine derivative having the general formula (I): Image (I) wherein A1 represents an unsubstituted or substituted pyridyl, piperidyl, piperidino, morpholinyl, morpholino, thiomorpholinyl, thiomorpholino or piperazinyl group, a substituted alkyl group having 1 to 8 carbon atoms, a substituted cycloalkyl group having 4 to 8 carbon atoms, a substituted cycloalkyl group having 4 to 8 carbon atoms, or an unsubstituted or substituted alkoxyl group having 1 to 8 carbon atoms; X1 represents a hydrogen or halogen atom; Y1 represents -CONH-, -NHCO-, -CONHCH2-, -(CH2)n- or -COO-, in which n is an integer ranging from 0 to 4; and Z1 represents -CH=CH-, -S-CH2-, -S- or -CH2-CH2-; or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable carrier therefor.
Arisaka Harumi
Makino Shingo
Shoji Masataka
Yamamoto Hiroshi
Yoshimoto Ryota
Ajinomoto Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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