Piperidine derivatives as neurokinin antagonists

Details Piperidine derivatives as neurokinin antagonists Piperidine derivatives as neurokinin antagonists

C - Chemistry, Metallurgy

07

D

C07D 211/52 (2006.01) A61K 31/4465 (2006.01) A61K 31/451 (2006.01) A61K 31/4525 (2006.01) A61K 31/495 (2006.01) C07D 211/14 (2006.01) C07D 211/58 (2006.01) C07D 295/145 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2198238

The invention relates to compounds of formula (I), wherein X, i, j, n, n', A, A', R2, R3, and U are as decribed herein. The compounds of the invention are NK1 or NK2 or NK3 receptor antagonists and as such are useful in the treatment of diseases such as asthma.

L'invention concerne des composés représentés par la formule (I) dans laquelle X, i, j, n, n', A, A', R2, R3 et U ont la signification donnée dans la description. Ces composés sont des antagonistes des récepteurs NK1, NK2 ou NK3 et, de ce fait, sont utiles pour le traitement de maladies, telles que l'asthme.

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