Piperidine derivatives, their preparation and their...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/445 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2064924

- 33 - ABSTRACT A compound which is a piperidine derivative of general formula (I) Image (I) in which R1 represents a hydrogen atom, a linear or branched (C1-6)alkyl group or a cyclo(C3-8)alkyl group, X represents an oxygen atom, a sulphur atom or a group of general formula N-R3 in which R3 is a hydrogen atom, or a linear or branched (C1-8)alkyl, cyclo(C3-6)alkyl, cyclo(C3-6)alkylmethyl, (C1-4)alkoxy-(C1-4)alkyl, phenyl, pyridin-4-yl, pyridin-3-yl, pyridin-4-ylmethyl or pyridin-3-ylmethyl group and Z represents a hydrogen or fluorine atom and acid addition salts thereof with pharmaceutically acceptable acids, can be used for the treatment and prevention of disorders in which 5-HT receptors are involved.

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