C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/444 (2006.01) A61K 31/4709 (2006.01) A61P 11/06 (2006.01) C07D 401/04 (2006.01)
Patent
CA 2554465
The use of CCR3 antagonists of the formula (I) or a pharmaceutically acceptable salt thereof for the treatment of asthma is disclosed, as well as novel compounds of the formula (II), pharmaceutical compositions comprising them, and their use in the treatment of asthma, wherein R, Ra, X, Xa, R1, R2, R2a, R14, R14a, R16 and n are as defined in the specification.
L'invention porte sur l'utilisation d'antagonistes de CCR3 de formule (I) ou sur un sel de ceux-ci acceptable d'un point de vue pharmaceutique dans le traitement de l'asthme, ainsi que sur de nouveaux composés de formule (II), sur des compositions pharmaceutiques les comprenant, et sur leur utilisation dans le traitement de l'asthme, R, R?a¿, X, X?a¿, R?1¿, R?2¿, R?2a¿, R?14¿, R?14a¿, R?16¿ et n étant tels que définis dans le descriptif.
Cao Jianhua
Dong Youhao
Gilbert Eric J.
Huang Ying
Kelly Joseph M.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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