Piperidines and piperazines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/06 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 211/18 (2006.01) C07D 211/22 (2006.01) C07D 295/096 (2006.01) C07D 319/18 (2006.01) C07D 401/06 (2006.01) C07D 405/00 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2126719

Abstract Piperidine and piperazine derivatives of the formula I Image I, in which R1 and R2 are H or A, R3, R4 and R5 in each case independently of one another are H, Hal, OH, OA, OAc, NO2, NH2, NHAc, NHSO2A or CN, or R3 and R4 together are also -O-(CH2)m-O-, n is 0, 1 or 2 X is O or CH2, if n = 0 or 2, or CH2, NH, NA or NAc, if n = 1, Y is CH or N m is 1 or 2 Hal is F, Cl, Br or I, A is alkyl having 1-6 C atoms and Ac is alkanoyl having 1-8 C atoms, aralkanoyl having 1-10 C atoms or aroyl having 7-11 C atoms, and their physiologically acceptable salts show anti- arrhythmic effects.

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