C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/34 (2006.01) A61K 31/40 (2006.01) A61K 31/451 (2006.01) A61K 31/496 (2006.01) A61P 25/28 (2006.01) C07D 207/08 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 241/04 (2006.01) C07D 401/06 (2006.01) C07D 471/08 (2006.01)
Patent
CA 2584504
Compounds of formula (I), selectively inhibit production of A.beta. (1-42) and hence are useful in treatment or prevention of disease assocaited with deposition of .beta. -amyloid in the brain.
La présente invention décrit des composés de formule (I) qui inhibent de façon sélective la production de A.beta. (1-42), et peuvent donc être employés dans le traitement prophylactique ou thérapeutique de maladies associées au dépôt de .beta.-amyloïde dans le cerveau.
Hannam Joanne Clare
Kulagowski Janusz Jozef
Madin Andrew
Ridgill Mark Peter
Seward Eileen Mary
Merck Sharp & Dohme Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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