Piperidinium and pyrrolidinium derivatives as ligands for...

Details Piperidinium and pyrrolidinium derivatives as ligands for... Piperidinium and pyrrolidinium derivatives as ligands for...

C - Chemistry, Metallurgy

07

D

C07D 211/46 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/452 (2006.01) A61P 11/00 (2006.01) C07D 207/08 (2006.01) C07D 211/22 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2526991

Compounds of formula (I) in salt or zwitterionic form wherein, wherein R1, R2, R3, R4, R5, J, L and M have the meanings as indicated in the specification, are useful for treating conditions that are mediated by the muscarinic M3 receptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

L'invention concerne des composés représentés par la formule I sous forme de sel ou de zwitterion, dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, J, L et M sont tels que décrits dans les spécifications, et utilisés dans le traitement d'états médiés par le récepteur muscarinique M3. L'invention concerne également des compositions pharmaceutiques contenant lesdidts composés, ainsi qu'un procédé de préparation desdits composés.

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