Piperidino-phthalazines

Details Piperidino-phthalazines Piperidino-phthalazines

C - Chemistry, Metallurgy

07

D

260/264.3

C07D 401/04 (2006.01) C07D 211/22 (2006.01) C07D 211/26 (2006.01) C07D 211/28 (2006.01) C07D 211/34 (2006.01) C07D 211/46 (2006.01) C07D 213/38 (2006.01) C07D 213/40 (2006.01) C07D 213/42 (2006.01) C07D 237/30 (2006.01) C07D 237/32 (2006.01)

Patent

CA 1114379

Abstract The invention relates to new phthalazines of the formula Image and the pharmaceutically acceptable salts thereof, wherein R is lower alkyl and Y is attached to the 3- or 4- position of the piperidino ring and represents a group of the formula -X-(CHR1)m-Z wherein R1 is hydrogen or lower alkyl, m is 1 or 2 (when m is 2, each R1 may be the same or different), X is oxygen or a direct link (when m is l, X is a direct link), and Z is selected from -OCONR4R5 -N(R2))COR3 -N(R2)SO2R3 -N(R2)CON4R5 and -N(R2)COOR3 where R2 is hydrogen or alkyl; R3 is alkyl, phenethyl, benzyl, phenyl or pyridyl; R4 and R5 are each hydrogen or a group as defined for R3. Several pro- cesses for preparing same are described. The new compounds are phosphodi- esterase inhibitors and cardiac stimulants.

314085

Affiliated with

Also associated with

Rating

Piperidino-phthalazines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Piperidino-phthalazines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Piperidino-phthalazines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1082197