C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/72 (2006.01) A61K 31/519 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/08 (2006.01) A61P 5/28 (2006.01) A61P 35/00 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2490818
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
La présente invention concerne des composés constituant des inhibiteurs de l'enzyme dipeptidyl peptidase-IV ("inhibiteurs de la DP-IV") et utilisés dans le traitement ou la prévention des maladies associées à l'enzyme dipeptidyl peptidase-IV, par exemple le diabète et, en particulier, le diabète de type 2. L'invention concerne également des compositions pharmaceutiques contenant ces composés, et l'utilisation de ces composés et compositions dans la prévention ou le traitement des maladies associées à l'enzyme dipeptidyl peptidase-IV.
Edmondson Scott D.
Mathvink Robert J.
Weber Ann E.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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