Piperidino-quinazolines

Details Piperidino-quinazolines Piperidino-quinazolines

C - Chemistry, Metallurgy

07

D

260/253

C07D 239/72 (2006.01) A61K 31/505 (2006.01) C07D 211/46 (2006.01)

Patent

CA 1088068

A B S T R A C T The invention relates to new compounds of the formula Image (I) wherein R is lower alkyl; and X is a group of the formula:- -0-alk-OR1 wherein "alk" represents an ethylene group optionally substituted by 1 or lower alkyl groups and R1 is hydrogen; lower alkyl; C3-C6 cycloalkyl; or a group of the formula: Image wherein R2 and R3 each independently represent hydrogen, lower alkyl, lower alkoxy, halogen, CF3, -CONR4R5 or -SO2NR4R5 wherein R4 and R5 each independent- ly represent hydrogen or lower alkyl; and a the pharmaceutically acceptable acid addition salts thereof; and to a process for preparing same. The new com- pounds are anithypertensive and cardiovascular system regulators.

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