Piperidinoalkyl derivatives of purines

Details Piperidinoalkyl derivatives of purines Piperidinoalkyl derivatives of purines

C - Chemistry, Metallurgy

07

D

260/242.3, 260/2

C07D 473/34 (2006.01)

Patent

CA 1062708

ABSTRACT OF THE DISCLOSURE New piperidinoalkyl derivatives of purine and their process of preparation are provided of formula (I) Image (I) wherein R1 is a hydrogen atom or a lower alkyl radical, R2 is a hydrogen atom, a lower alkyl radical, a hydroxy-lower-alkyl radical or a cycloalkyl radical or R1 and R2, together with the nitrogen atom to which they are attached, form a heterocyclic ring, and R3 is a hydrogen or halogen atom or a lower alkyl or lower alkoxy radical; and the acid addition salts thereof with pharmacologically compatible acids; the new derivatives suppress the liberation and action of histamine; they also possess an anti-hypertensive action.

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