Piperidinoyl-pyrrolidine and piperidinoyl-piperidine compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/06 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61P 3/04 (2006.01) A61P 15/00 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2617654

The present invention relates to a class of compounds of general formula (I) and the salts, hydrates, solvates, polymorphs and prodrugs wherein n, R6, R7 and R10 are as defined herein and especially to MCR4 agonist compounds of formula (I), to their use in medicine, particularly in the treatment of sexual dysfunction and obesity, to intermediates useful in their synthesis and to compositions containing them.

La présente invention concerne une classe de composés représentés par la formule générale (I) et les sels, les hydrates, les polymorphe et les promédicaments, dans cette formule, n, R6, R7 and R10 étant tels que définis dans les spécifications, et en particulier de composés agonistes MCR4 représentés par la formule (I), leur utilisation en médecine, en particulier dans le traitement de dysfonctionnement sexuel et de l'obésité, des intermédiaires utiles dans leur synthèse et des compositions contenant ces composés.

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