C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/18 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61P 25/28 (2006.01) C07D 211/38 (2006.01) C07D 241/04 (2006.01) C07D 295/155 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2702837
The present invention relates to compounds of Formula (I) as shown below, wherein the definitions of Het, R0, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula (I) are useful for the treatment of diseases associated with .gamma.-secretase activity, including Alzheimer's disease.
La présente invention concerne des composés de formule (I) tels que représentés ci-dessous, les définitions de Het, R0, R1, R2, R3, R4, R5, R6, R7, R8, et R9 étant explicitées dans la spécification. Les composés de formule (I) sont utiles dans le traitement de maladies associées à l'activité de la ?-secrétase, y compris la maladie d'Alzheimer.
Janssen Pharmaceutica N.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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