Piperidinyl prostaglandin analogs as ocular hypotensive agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/76 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2569464

A compound comprising (I) or a pharmaceutically acceptable salt or a prodrug thereof is disclosed herein. Y and R are described in detail herein. A compound having an .omega. chain comprising (II) or a derivative thereof, or a pharmaceutically acceptable salt or a prodrug thereof, is disclosed. Derivatives, salts and prodrugs are identified and described in detail. Methods of treating certain conditions or diseases, and compositions and medicaments related thereto are also contemplated.

L'invention concerne un composé contenant (I), ou un sel ou un prodrogue pharmaceutiquement acceptable de ce dernier. Y et R sont définis en détail. L'invention concerne également un composé ayant une chaîne .omega. contenant (II) ou un dérivé de ce dernier, ou un sel ou un prodrogue pharmaceutiquement acceptable de ce dernier. Les dérivés, sels et prodrogues sont identifiés et décrits en détail. L'invention concerne enfin des procédés de traitement de certains états ou certaines maladies et des compositions et médicaments correspondants.

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