C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/04 (2006.01) A61K 31/427 (2006.01) A61P 35/00 (2006.01) C07D 231/00 (2006.01) C07D 253/00 (2006.01) C07D 417/14 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2511506
This invention relates to compounds of formula (I) and (II) that are useful in treating vascular endothelial growth factor (VEGF)-mediated disorders, particularly endometriosis and acute macular degenerative disorder. The invention also relates to a topical system for the treatment of acute macular degenerative disorder comprising a VEGF inhibitor.
La présente invention se rapporte à des composés de formule (I) et (II), que l'on utilise dans le traitement de troubles induits par le facteur de croissance de l'endothélium vasculaire (VEGF), plus particulièrement l'endométriose et la dégénérescence maculaire aiguë. L'invention se rapporte également à un système topique pour le traitement de la dégénérescence maculaire aiguë comprenant un inhibiteur du VEGF.
Knox Peter
Lentfer Heike
O'sullivan Michele
Dspi Limited
Kirby Eades Gale Baker
Metris Therapeutics Limited
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