Piperidinylcarbonyl-pyrrolidines and their use as...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/06 (2006.01) A61K 31/454 (2006.01) A61P 15/00 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2555800

The present invention relates to a class of melanocortin MCR4 agonists of general formula (I) wherein R', R2, R3, R4 and R5 are as defined herein and especially to selective MCR4 agonist compounds, tot heir use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes.

La présente invention a trait à une classe d'agonistes MCR4 de la mélanocortine de formule générale (I), dans laquelle R', R?2¿, R?3¿, R?4¿ et R?5¿ sont tels que définis dans la description et particulièrement à des composés agonistes MCR4 sélectifs, à leur utilisation en médecine, à des compositions les contenant, à des procédés pour leur préparation et à des intermédiaires utilisés dans de tels procédés.

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