(piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl,...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 211/44 (2006.01) A61K 31/445 (2006.01) A61P 25/06 (2006.01) C07D 211/54 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2518839

The present invention relates to compounds of formula 1: and pharmaceutically acceptable acid addition sails thereof. The compounds of the present invention are useful for activating 5-HTIF receptors, inhibiting neuronal protein extravasation, and for the treatment or preverition of migraine in mammals, particularly humans.

La présente invention concerne des composés correspondant à la formule (I), ainsi que des sels d'addition d'acide de ceux-ci pharmaceutiquement acceptables. Lesdits composés peuvent être utilisés pour l'activation des récepteurs 5-HT<SB>IF</SB>, pour l'inhibition de l'extravasion de protéine neuronale, et pour le traitement ou la prévention de la migraine chez les mammifères, en particulier chez l'homme.

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