Placental-derived prostate growth factors

Details Placental-derived prostate growth factors Placental-derived prostate growth factors

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) C07K 1/107 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01) C07K 17/08 (2006.01) C12N 1/21 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2268746

Polypeptide growth factors, termed PDPFs, are described which are derived from placental tissue and promote the proliferation, growth and survival of prostate cells and epithelial cells. Nucleic acid molecules encoding the polypeptides are also described which are useful in recombinant methods for the production of the polypeptides.

L'invention concerne des facteurs de croissance polypeptidiques appelés PDPF, lesquels sont dérivés de tissus placentaires et stimulent la prolifération, la croissance et la survie de cellules de la prostate et de cellules épitéliales. L'invention concerne également des molécules nucléotidiques codant les polypeptides, lesquelles sont utiles dans des techniques de recombinaison destinées à la production des polypeptides.

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