C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/415 (2006.01) A61K 8/64 (2006.01) A61K 8/97 (2006.01) A61K 36/899 (2006.01) A61K 38/08 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 14/78 (2006.01)
Patent
CA 2605078
The present invention describes novel plant derived elastin-like peptides and peptidomimetics that may serve as functional ligands for elastin receptors and stimulate elastogenesis. The novel plant derived peptides provide an alternative (non-animal derived) source of GXXPG (SEQ ID NO. 2) containing peptides. The present invention also describes therapeutic compositions containing novel plant derived peptides or peptidomimetics useful in stimulating elastogenensis and capillary dilatation. The therapeutic compositions of the present invention that comprise novel plant derived peptides or peptidomimetics may be combined with other therapeutic agents.
La présente invention a trait à de nouveaux peptides et peptidomimétiques de type élastine dérivés de plantes pouvant servir de ligands fonctionnels pour des récepteurs d'élastine et la stimulation d'élastogenèse. Les nouveaux peptides dérivés de plantes fournissent une source alternative (d'origine non animale) de peptides contenant la séquence de GXXPG (SEQ ID NO. 2). La présente invention a également trait à des compositions thérapeutiques contenant de nouveaux peptides et peptidomimétiques dérivés de plantes utiles dans la stimulation d'élastogenèse et la dilatation capillaire. Les compositions thérapeutiques de la présente invention comportant de nouveaux peptides ou peptidomimétiques dérivés de plantes peuvent être combinées avec d'autres agents thérapeutiques.
Hinek Aleksander
Jimenez Felipe
Mitts Thomas F.
Borden Ladner Gervais Llp
Human Matrix Sciences Llc
The Hospital For Sick Children
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