Plant pathogen resistance genes and uses thereof

Details Plant pathogen resistance genes and uses thereof Plant pathogen resistance genes and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) A01H 5/00 (2006.01) A01H 5/10 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C07K 14/37 (2006.01) C07K 14/415 (2006.01) C12N 15/10 (2006.01) C12N 15/82 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2215496

The tomato Cf-2 gene has been cloned and its sequence provided, along with the encoded amino acid sequence. DNA encoding the polypeptide, and alleles, mutants and derivatives thereof, may be introduced into plant cells and the encoded polypeptide expressed, conferring pathogen resistance on plants comprising such cells and descendants thereof. The Cf-2 sequence comprises leucine rich repeats and the presence of such repeats enables identification of other plant pathogen resistance genes. Homologies to Cf-9 reveal motifs useful in the identification of other plant pathogen resistance genes.

On a cloné le gène Cf-2 de la tomate et on a établi sa séquence, ainsi que la séquence codée d'acides aminés. L'ADN codant le polypeptide, ainsi que ses allèles, ses mutants et ses dérivés, peuvent être introduits dans des cellules végétales et le polypeptide codé peut être exprimé, ce qui confère une résistance aux agents pathogènes végétaux comprenant lesdites cellules, ainsi qu'à leurs descendants. La séquence de Cf-2 comprend des répétitions riches en leucine et la présence de ces répétitions permet d'identifier d'autres gènes de résistance aux agents pathogènes végétaux. Des homologies de Cf-9 révèlent des motifs utiles pour identifier d'autres gènes de résistance aux agents pathogènes végétaux.

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