Plant retinoblastoma-associated proteins

Details Plant retinoblastoma-associated proteins Plant retinoblastoma-associated proteins

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) A01H 5/00 (2006.01) C07K 14/415 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2257828

The present invention is based on the isolation and characterization of a plant cell DNA sequence encoding for a retinoblastoma protein. Such finding is based on the structural and functional properties of the plant retinoblastoma protein as possible regulator of the cellular cycle, of the cellular growth and of the plant cellular differentiation. For this reason, among other aspects, it is claimed the use of retinoblastoma protein or the DNA sequence which encodes for it in the growing control of vegetable cells, plants and/or vegetable virus, as well as the use of vectors, cells, plants or animals, or animal cells modified through the manipulation of the control route based on plant retinoblastoma protein.

La présente invention est fondée sur l'isolation et la caractérisation d'une séquence d'ADN de cellules végétales codant une protéine de rétinoblastome. Une telle découverte se base sur les propriétés structurelles et fonctionnelles de la protéine de rétinoblastome végétale comme un régulateur possible du cycle cellulaire, de la croissance cellulaire et de la différenciation cellulaire de la plante. Pour cette raison, on revendique, en autres, l'utilisation de la protéine de rétinoblastome, ou de la séquence d'ADN qui la code, dans la régulation de la croissance de cellules végétales, de plantes et/ou de virus végétaux, ainsi que l'utilisation de vecteurs, cellules, plantes ou animaux, ou cellules animales, présentant une modification obtenue par la manipulation de la voie de régulation basée sur la protéine de rétinoblastome végétale.

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