Plant sterol acyltransferases

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/82 (2006.01) C12N 9/10 (2006.01)

Patent

CA 2381901

The present invention is directed to lecithin: cholesterol acyltransferase- like polypeptides (LCAT) and acyl CoA: cholesterol acyltransferases-like polypeptides (ACAT). The invention provides polynucleotides encoding such cholesterol: acyltransferases-like polypeptides, polypeptides encoded by such polynucleotides, and the use of such polynucleotides to alter sterol composition and oil production in plants and host cells. Also provided are oils produced by the plants and host cells containing the polynucleotides and food products, nutritional supplements, and pharmaceutical composition containing plants or oils of the present invention. The polynucleotides of the present invention include those derived from plant sources.

La présente invention concerne des polypeptides de type lécithine cholestérol acyltransférase (LCAT) et des polypeptides de type acyl-CoA-cholestérol acyltransférase (ACAT). L'invention concerne des polynucléotides codant pour ces polypeptides de type cholestérol acyltransférase, les polypeptides codés par lesdits polynucléotides et l'utilisation de ces derniers pour modifier la composition stérol et la production d'huile dans des végétaux et des cellules hôtes. L'invention concerne également des huiles produites par les plantes et les cellules hôtes contenant ces polynucléotides et les produits alimentaires, les suppléments nutritionnels et les compositions pharmaceutiques contenant les plantes ou les huiles de l'invention. Parmi les polynucléotides de l'invention figurent ceux dérivés de sources végétales.

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