Plants capable of metabolizing chemical substances and use...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A01H 1/00 (2006.01) A01H 5/00 (2006.01) B09C 1/00 (2006.01) B09C 1/10 (2006.01) C12N 5/04 (2006.01) C12N 9/02 (2006.01) C12N 15/82 (2006.01) C12Q 1/26 (2006.01)

Patent

CA 2344674

Transgenic plants capable of metabolizing drugs which are constructed by transferring a drug-metabolizing P450 molecular species into plants. These plants are capable of detoxifying and metabolizing foreign compounds such as drugs, poisons and environmental loads and endocrine disruptors including pesticides. Thus, they are highly useful when applied to field crops, etc. Also, a method for screening the drug-metabolizing P450 molecular species is provided.

L'invention concerne des plantes transgéniques capables de métaboliser des substances toxiques, lesquelles plantes sont obtenues par transfert dans les plantes d'une espèce moléculaire P450 métabolisant les substances toxiques. Ces plantes sont capables de désintoxiquer et de métaboliser des composés étrangers tels que les substances toxiques, les poisons, les contaminants de l'environnement et les produits chimiques qui perturbent le système endocrinien, notamment les pesticides. Ainsi, ces plantes sont très utiles dans le domaine des grandes cultures. L'invention concerne également un procédé de criblage de l'espèce moléculaire P450 métabolisant les substances toxiques.

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