C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01) C12N 15/72 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2067237
- 36 - ABSTRACT A plasmid for the production of an inhibitory protein for phospholipase A2 originated from inflammatory sites, a microbial cell transformed with the plasmid, the protein, and a method of producing same by culturing with the cell, and a pharmaceutical composition for a suppression of allergic reactions comprising same as an active ingredient, are provided. The plasmid comprises a DNA sequence encoding an inhibitory protein for phospholipase A2 originated from inflammatory sites of rat and human, and a DNA sequence that acts as a promotor to regulate the expression of the protein. An Eschericia coli cell is mainly used as the host cell.
Azuma Chieko
Imaizumi Atsushi
Inoue Keizo
Kudo Ichiro
Murakami Makoto
Azuma Chieko
Imaizumi Atsushi
Inoue Keizo
Kudo Ichiro
Mcfadden Fincham
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