Plasmid entrapping multilamellar liposomes

Details Plasmid entrapping multilamellar liposomes Plasmid entrapping multilamellar liposomes

C - Chemistry, Metallurgy

12

N

C12N 15/88 (2006.01) A61K 9/127 (2006.01)

Patent

CA 2200012

A plasmid entrapping multilamellar liposome for introducing a gene into cells, which liposome has constitutive lipids of TMAG; DOPC or DDPC; and DOPE or DLPE and in a molar ratio of 1: 2 - 3: 2 - 1 in case of lipid combination of TMAG, DOPC and DOPE, or 1: 2:2 in case of lipid combination of TMAG, DDPC or DOPC and DLPE.

Liposome multilamellaire renfermant des plasmides pour l'introduction de gènes dans les cellules, lequel liposome possède les lipides constitutifs suivants : TMAG; DOPC ou DDPC; et DOPE ou DLPE et dans un rapport molaire de 1:2 - 3:2 - 1 dans le cas de la combinaison de lipides TMAG, DOPC et DOPE, ou 1:2:2 dans le cas de la combinaison de lipides TMAG, DDPC ou DOPC et DLPE.

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