A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2268752
Improved vaccines are disclosed. The improved vaccines include a nucleotide sequence that encodes a coding sequence that comprises an immunogenic target protein linked to or comprising an intracellular cellular targeting sequence, the coding sequence being operably linked to regulatory elements. Methods of immunizing individuals are disclosed.
Cette invention se rapporte à des vaccins perfectionnés comportant une séquence nucléotidique qui code une séquence codante comprenant une protéine cible immunogénique liée à (ou comprenant) une séquence de ciblage intracellulaire, ladite séquence codante étant fonctionnellement liée à des éléments régulateurs. L'invention se rapporte également à des procédés d'immunisation d'individus.
Madaio Michael
Weiner David B.
Williams William V.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Trustees Of The University Of Pennsylvania
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