C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/15 (2006.01) A61K 38/17 (2006.01) A61K 38/36 (2006.01) A61K 39/44 (2006.01) A61K 47/48 (2006.01) C07H 21/04 (2006.01) C07K 14/46 (2006.01) C07K 14/81 (2006.01) C07K 16/38 (2006.01)
Patent
CA 2328431
The invention provides novel single stage competitive inhibitors of plasmin from the Australian brown snake Pseudonaja textilis textilis. The invention also features polynucleotides and polynucleotide homologues encoding these inhibitors. Pharmaceutical compositions containing the plasmin inhibitors of the invention are also disclosed as well as methods useful for treatment of blood loss.
Cette invention a trait à de nouveaux inhibiteurs compétitifs, à stade unique, de la plasmine, tirés du serpent brun australien Pseudonaja textilis textilis. Elle porte également sur des polynucléotides et des homologues de polynucléotide codant ces inhibiteurs. Elle concerne, en outre, des compositions pharmaceutiques contenant ces inhibiteurs de plasmine ainsi que des méthodes efficaces de traitement de la perte sanguine.
Gaffney Patrick Joseph
Lavin Martin Francis
Masci Pantaleone Paul
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
National Institute Of Biological Standards And Control United Kingdom
The University Of Queensland
Venomics Pty Limited
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