C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/81 (2006.01) A61K 31/196 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/4025 (2006.01) A61K 31/404 (2006.01) A61K 31/4418 (2006.01) A61K 31/4525 (2006.01) A61P 1/16 (2006.01) A61P 7/02 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 9/14 (2006.01) A61P 11/00 (2006.01) A61P 13/12 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 27/02 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61P 43/00 (2006.01) C07D 213/56 (2006.01) C07D 307/42 (2006.01) C07D 307/54 (2006.01)
Patent
CA 2757615
The present invention provides a novel compound having plasminogen activator inhibitor-1 inhibitory activity, and an inhibitor of PAI-1 comprising the compound as an active ingredient. The present invention also provides a pharmaceutical composition having an inhibitory action on PAI-1 activity and being efficacious in the prevention and treatment of various diseases whose onset is associated with PAI-1 activity.
L'invention concerne un nouveau composé présentant une activité d'inhibition de l'inhibiteur de l'activateur du plasminogène 1 (PAI-1) ainsi qu'un inhibiteur de PAI-1 dont l'ingrédient actif principal est le composé susmentionné. L'invention concerne également une composition pharmaceutique dont l'ingrédient actif principal est le composé susmentionné inhibiteur de PAI-1, efficace dans la cure ou la prévention de diverses maladies provoquées par l'activité de PAI-1.
Maeda Akihisa
Miyata Toshio
Murano Kenji
Yamaoka Nagahisa
Marks & Clerk
Renascience Co. Ltd.
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