Plasmodium proteases inhibitors and in silico screening...

Details Plasmodium proteases inhibitors and in silico screening... Plasmodium proteases inhibitors and in silico screening...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4162 (2006.01) A61K 31/4184 (2006.01) A61K 31/4425 (2006.01) A61K 31/4709 (2006.01) A61K 31/5025 (2006.01) A61P 33/06 (2006.01) C07D 213/85 (2006.01) C07D 235/14 (2006.01) C07D 401/12 (2006.01) C12Q 1/02 (2006.01) C12Q 1/37 (2006.01) C40B 30/02 (2006.01)

Patent

CA 2686584

The invention relates to the field of parasitology. Methods for screening method for identifying inhibitors of Plasmodium and compounds identified by these methods, including more particularly inhibitors of Plasmodium subtilisin-like proteases, are described. The invention also concerns anti-malaria compounds, anti-malaria compositions, and uses thereof for preventing, treating, improving, and/or alleviating a Plasmodium infection in a subject, and more Plasmodium vivax and/or by Plasmodium falciparum human infections.

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