C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/30 (2006.01) A61K 39/015 (2006.01) C07K 14/445 (2006.01) C07K 14/705 (2006.01) C07K 16/20 (2006.01) C07K 16/28 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2164428
This invention is directed to novel species-specific P. vivax malarial peptide antigens which are proteins or fragments of proteins secreted into the plasma of a susceptible mammalian host after infection, and to monoclonal or polyclonal antibodies directed against those antigens. The peptide antigens, monoclonal antibodies, and/or polyclonal antibodies are utilized in assays used to diagnose malaria, as well as to determine whether Plasmodium vivax is the species responsible for the infection.
Cette invention concerne de nouveaux antigènes peptidiques paludéens de P. vivax spécifiques d'une espèce, qui sont des protéines ou des fragments de protéines sécrétés dans le plasma d'un mammifère hôte sensible après l'infection, ainsi qu'à des anticorps monoclonaux ou polyclonaux dirigés contre ces antigènes. Les antigènes peptidiques et les anticorps monoclonaux et/ou polyclonaux sont utilisés dans des dosages permettant de diagnostiquer le paludisme, ainsi que pour déterminer si le Plasmodium vivax est l'espèce responsable de l'infection.
Fetherstonhaugh & Co.
New York University
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