Plaster containing an active substance

Details Plaster containing an active substance Plaster containing an active substance

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 31/21 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2177970

The proposed plaster containing an active substance for the controlled release of active substances comprises a backing layer, a reservoir layer adjacent to it which contains active substance and softens at body temperature, a membrane which controls the release of the active substance, an adhesive system with which the plaster can be fixed to the skin, and a removable protective layer. The proposed plaster is characterized by the fact that the reservoir layer which softens at body temperature is separated from the control membrane by a device made of a material which is not permeable to the active substance and extends right across the mutually opposing surfaces of the reservoir and membrane and has at least one passage for the reservoir layer.

L'invention concerne un emplâtre contenant des principes actifs, permettant la libération contrôlée de principes actifs, qui comprend une couche dorsale, une couche réservoir placée sur la couche dorsale de manière adjacente, qui contient les principes actifs, et se ramollit à la température du corps, une membrane qui régule la libération des principes actifs, un système adhésif qui permet le maintien de l'emplâtre en place sur la peau, et une couche protectrice amovible. Cet emplâtre se caractérise en ce que la couche réservoir qui se ramollit à la température du corps est séparée de la membrane de régulation par un dispositif réalisé dans un matériau imperméable au principe actif, qui s'étend sur l'ensemble des surfaces du réservoir et de la membrane qui se font face, et qui comprend au moins un passage pour la couche réservoir qui se ramollit à la température du corps.

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