Plaster which contains steroids, and a method for the...

Details Plaster which contains steroids, and a method for the... Plaster which contains steroids, and a method for the...

A - Human Necessities

61

K

A61K 31/567 (2006.01) A61K 9/70 (2006.01) A61K 31/565 (2006.01) A61P 15/12 (2006.01)

Patent

CA 2336654

Medicinal self-adhesive composition for transdermal applica-tion of an estrogen in combination with a gestagen, contain-ing (a) 25-90%-wt. of a self-adhesive acrylate copolymer, (b) 1-15%-wt. of a film-forming acrylate copolymer, characterized in that acid-reacting, functional groups are contained, (c) 1-30%-wt. of tack-increasing additives, (d) 0.2-2.0%-wt. of estrogen and (e) 1-5%-wt. of gestagen.

L'invention concerne une composition auto-adhésive médicale, destinée à l'application transdermique d'un oestrogène en combinaison avec un progestatif, qui contient: (a) entre 25 et 90 % en poids d'un copolymère d'acrylate auto-adhésif; (b) entre 1 et 15 % en poids d'un copolymère d'acrylate filmogène, caractérisé en ce qu'il comprend des groupes fonctionnels à réaction acide; (c) entre 1 et 30 % en poids d'additifs renforçant l'adhérence; (d) entre 0,2 et 2,0 % en poids d'oestrogène et (e) entre 1 et 5 % en poids de progestatif.

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