Platelet adp receptor inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 513/04 (2006.01) A61K 31/54 (2006.01) C07D 277/00 (2006.01) C07D 285/00 (2006.01) C07D 513/14 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2318199

The invention relates to novel compounds of formula (I) containing fused heterocyclic ring systems which are effective platelet ADP receptor inhibitors. Such compounds including pharmaceutically acceptable salts are useful in various pharmaceutical compositions for the prevention and/or treatment of cardiovascular disease particularly those related to thrombosis.

L'invention se rapporte à de nouveaux composés correspondant à la formule (I) et contenant des systèmes de cycles hétérocycliques fusionnés qui constituent des inhibiteurs efficaces des récepteurs d'ADP des plaquettes. Ces composés, qui comprennent des sels pharmaceutiquement acceptables, sont utiles dans diverses préparations pharmaceutiques destinées à la prévention et/ou au traitement des maladies cardio-vasculaires, en particulier de celles liées à la thrombose.

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