Platelet-aggregation inhibitors

Details Platelet-aggregation inhibitors Platelet-aggregation inhibitors

C - Chemistry, Metallurgy

07

K

530/5.02, 167/10

C07K 5/02 (2006.01) A61K 31/155 (2006.01) A61K 31/16 (2006.01) C07C 279/14 (2006.01) C07K 5/072 (2006.01)

Patent

CA 1326326

NOVEL PLATELET-AGGREGATION INHIBITORS Abstract of the Disclosure Novel peptide mimetic compounds are provided which have useful activity as inhibitors of platelet aggregation. These compounds have the chemical structure Image wherein x = 6 to 10, y = 0 to 4, Z = H, COOH, CONH2 or C1-6 alkyl, Ar = phenyl, biphenyl or napthyl, each substituted with 1 to 3 methoxy groups, or an unsubstituted phenyl, biphenyl, napthyl, pyridyl or thienyl group, and Asp = aspartic acid residue.

606133

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