Platelet-aggregation inhibitors

Details Platelet-aggregation inhibitors Platelet-aggregation inhibitors

C - Chemistry, Metallurgy

07

K

530/5.06, 530/5.

C07K 5/02 (2006.01) A61K 38/05 (2006.01) C07D 209/20 (2006.01) C07D 213/40 (2006.01) C07K 5/072 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2040947

Novel peptide mimetic compounds are provided which have useful activity as inhibitors of platelet aggregation. These compounds have the chemical structure (see formula I) wherein x = 4 to 8, y = 0 to 4, W = CH2-CH2 or CH=CH, Z = H, COOH, CONH2, CH2OH, CO2R, CH2OR or C1-6 alkyl, R = C1-6 alkyl, Ar = a nitrogen-containing heterocyclic group other than pyridyl, and Asp = aspartic acid residue.

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