Platelet binding inhibitors

Details Platelet binding inhibitors Platelet binding inhibitors

C - Chemistry, Metallurgy

07

K

530/7, 530/5.1

C07K 5/10 (2006.01) C07K 7/00 (2006.01) C07K 14/745 (2006.01) C07K 14/75 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1306581

Case Docket No. APC 85-78 Express Mail Label No. B 77611926 ABSTRACT OF THE DISCLOSURE Peptides of the general formula H2N-(Ch)-Arg-Gly-Asp-(Cx)-H and the derivatives thereof described herein, wherein (Cx) and (Ch) each contains 1 to 20 amino acid residues and (Ch) contains at least one Lys or Arg residue, or at least one of each, inhibit platelet-fibrinogen binding and platelet-platelet aggregation and are thus useful inhibitors of cell adhesion.

521502

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