C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01)
Patent
CA 2564396
The present inventors have surprisingly discovered that platelets sequester angiogenic regulators and prevent their degradation. Thus, by analyzing levels of angiogenic regulators in platelets, it is now possible to detect angiogenic activity, even at an early stage. By monitoring for changes in angiogenic activity, the presence of cancer or other angiogenic diseases or disorders can be predicted.
Selon l'invention, les plaquettes peuvent séquestrer des régulateurs angiogéniques et empêcher leur dégradation. Ainsi, l'analyse des taux de régulateurs angiogéniques dans les plaquettes permet désormais de détecter une activité angiogénique, même à un stade précoce. La surveillance des modifications de l'activité angiogénique permet de diagnostiquer la présence d'un cancer ou d'autres maladies ou troubles angiogéniques.
Folkman Judah
Klement Giannoula
Children's Medical Center Corporation
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
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