Platelet-derived growth factor d, dna coding therefor, and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/49 (2006.01) C07K 16/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2349951

PDGF-D, a new member of the PDGF/VEGF family of growth factors, is described, as well as the nucleotide sequence encoding it, methods for producing it, antibodies and other antagonists to it, transfected and transformed host cells expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.

L'invention concerne PDGF-D, un nouveau membre de la famille PDGF/VEGF des facteurs de croissance, ainsi que la séquence nucléotidique codant pour ce facteur PDGF-D. Cette invention concerne également des procédés de production de ce facteur, des anticorps et d'autres antagonistes de celui-ci, des cellules hôtes transfectées et transformées qui l'expriment, des compositions pharmaceutiques qui le contiennent, et enfin l'utilisation de ce facteur dans des applications médicales et diagnostiques.

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