A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01)
Patent
CA 2269335
Platelet substitutes, comprising fibrinogen, or analogous products useful in therapy, comprise an insoluble carrier to which is bound an essentially non- degraded active protein including the sequence RGD. Such conjugates can be made by a conjugation process comprising 0.01 to 2.5 % by weight active fibrinogen, and no more than 50 % inactive fibrinogen.
Les substituts de plaquettes, contenant du fibrinogène ou des produits analogues utiles d'un point de vue thérapeutique, comprennent un support insoluble sur lequel est fixée une protéine active essentiellement non dégradée contenant la séquence RGD. Un procédé de conjugaison permet de préparer de tels conjugués comprenant de 0,01 à 2,5 % en poids de fibrinogène actif, et pas plus de 50 % de fibrinogène inactif.
Church Nicola Jane
Harris Roy
Heath David
Middleton Sarah Margaret
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Quadrant Drug Delivery Limited
Quadrant Healthcare (uk) Limited
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