C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/02 (2006.01) C12N 7/00 (2006.01) C12N 15/00 (2006.01)
Patent
CA 2401018
Methods for identifying genes and gene products involved in RNA modification (as depicted in Figure 2), and methods for screening test compounds or antibiotics for activity are provided. Additionally, the gene products identified in the methods, the genes that encode the gene products, modified sentinel molecules produced by the gene products, and compounds or antibiotics which inhibit the modification process are provided.
L'invention concerne des procédés d'identification de gènes et des produits de gènes impliqués dans la modification d'ARN (comme montré Figure 2), ainsi que des méthodes destinées au criblage d'activité de composés test ou d'antibiotiques. Elle concerne, en outre, les produits de gènes identifiés dans les méthodes, les gènes qui codent pour ces produits, des molécules sentinelles modifiées produites par ces produits, ainsi que des composés ou des antibiotiques qui permettent d'inhiber le processus de modification.
Beckman Kenneth
Mitchell Wayne
Roberts T. Guy
Fetherstonhaugh & Co.
Montclair Group
Tao Biosciences Llc
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