Platinum complex

Details Platinum complex Platinum complex

C - Chemistry, Metallurgy

07

F

167/119, 260/429

C07F 15/00 (2006.01) A61K 31/28 (2006.01)

Patent

CA 2005851

ABSTRACT OF THE DISCLOSURE A platinum complex having the following formula (I) is disclosed, Image (I) wherein R1 and R2 may be the same or different and each independently represents a methyl group or an ethyl group, and the configuration of 1,2-diaminocyclohexane is either cis-, trans-1-, trans-d-, or trans-d1-. The compounds possess excellent antitumor activity with a high therapeutic index and abundant water solubility, and thus are effective as an antitumor agent.

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