Platinum complex and antitumor agent

Details Platinum complex and antitumor agent Platinum complex and antitumor agent

C - Chemistry, Metallurgy

08

B

C08B 37/08 (2006.01) A61K 31/28 (2006.01) A61K 33/24 (2006.01) A61K 45/06 (2006.01) A61K 47/48 (2006.01) A61K 31/72 (1990.01)

Patent

CA 2118217

- 22 - ABSTRACT A platinum complex which comprises a cycloalkanediamine platinum (II) residue being coordinated with a carboxyl group and/or a sulfuric acid group of chondroitin sulfate containing chondroitin-4-sulfate as a main component, which is electrophoretically uniform and has a platinum content of 5 % by weight or less and a solubility in water at 20 °C of 10 mg/ml or more. A platinum complex having highly improved solubility in water and antitumor activity and organ selectivity to a liver, etc. is provided.

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