Platinum complexes

Details Platinum complexes Platinum complexes

C - Chemistry, Metallurgy

07

F

260/325, 260/335

C07F 15/00 (2006.01)

Patent

CA 1256115

NOVEL PLATINUM COMPLEXES Abstact of the Disclosure: Novel platinum complexes represented by the formula: Image (I) wherein A is alkylene having carbon atoms of from 1 to 3; R1, R2, R3 and R4 are the same or different and are hydrogen or alkyl having carbon atoms of from 1 to 4; X and Y are independently a halogen atom, or combined together to form Image ; and ?, m and n are independently 0 or 1, with the proviso that when n is 0, X and Y do not simultaneously represent a halogen atom, and a process for preparing the same are disclosed. These platinum complexes have high antitumor activity and low toxicity, and are easily soluble in water. Therefore, they are very useful as an antitumor agent.

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