Platinum complexes and antitumor agents containing them as...

Details Platinum complexes and antitumor agents containing them as... Platinum complexes and antitumor agents containing them as...

C - Chemistry, Metallurgy

07

F

167/119, 260/429

C07F 15/00 (2006.01) A61K 31/28 (2006.01) C07C 59/01 (2006.01) C07C 62/02 (2006.01) C07C 62/04 (2006.01)

Patent

CA 2012155

Novel platinum complexes of the formula: Image (I) wherein R1 and R2 each identically or differently is lower alkyl, or R1 and R2 taken together form -(CH2)m-, and m is an integer from 2 to 5, and antitumor agents comprising the compound (I), which is effective to cisplatin-resistant ascitic murine leukemia, murine leukemia, and solid tumor with slight hemotoxicity and nephrotoxicity.

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