Platinum complexes and their uses in therapy

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 15/00 (2006.01) A61K 9/127 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2456348

The present invention concerns novel platinum complexes in which at least one of the amine ligand is a non-planar heterocyclic aliphatic amine. The platinum complexes may be in a trans or cis configuration and were found to posses therapeutic activites. Thus, the present concerns novel platinum complexes, pharmaceutical compositions comprising them and other uses thereof.

La présente invention concerne des nouveaux complexes de platine dans lesquels au moins l'un des ligands amine est une amine aliphatique hétérocyclique. Ces complexes de platine peuvent présenter une configuration trans ou cis, et sont également dotés d'activités thérapeutiques. L'invention concerne des nouveaux complexes de platine, des compositions pharmaceutiques comprenant ces complexes, ainsi que d'autres utilisations de ces complexes.

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