Platinum complexes of single isomer neoalkyl acids

A - Human Necessities – 61 – K

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167/119, 260/520

A61K 31/28 (2006.01) A61K 9/127 (2006.01) C07C 53/128 (2006.01)

Patent

CA 1339034

This invention relates to pure single isomers of neoalkyl carboxylic acids and platinum complexes comprising the single isomer neoacids. The use of liposomes incorporating these complexes and used in anti-tumor chemotherapy is also described. A particularly preferred liposomal formulation comprising a saturated phosphatidylcholine is described.

608409

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