Platinum-diamine complexes, a process for the preparation...

Details Platinum-diamine complexes, a process for the preparation... Platinum-diamine complexes, a process for the preparation...

C - Chemistry, Metallurgy

07

F

260/429.4

C07F 15/00 (2006.01)

Patent

CA 1229618

A B S T R A C T =============== This invention relates to novel platinum compounds, a method for the preparation thereof, a pharmaceutical composition using the novel compounds and a method for the treatment of cancer using the pharmaceutical composition, wherein the platinum-(II)-diamine complexes are charac- terized by the formula Image wherein R1 and R2 are both ethyl or together with the carbon atom, to which they are bonded, a cyclohexyl group, R3 and R4 are both a hydrogen atom and X is a malonate group, an ethylmalonate group, a hydroxymalonate group, a carboxyphthalate group, a bischloro acetate group, a cyclobutane- 1,1-dicarboxylate group, a dinitrate group or an oxalate group or a sodium salt of these groups.

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